FUNCTIONAL AND STRUCTURAL DEFICITS OF THE DENTATE GYRUS NETWORK COINCIDE WITH EMERGING SPONTANEOUS SEIZURES IN AN SCN1A MUTANT DRAVET SYNDROME MODEL DURING DEVELOPMENT

Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development

Show Your Pride Dravet syndrome (DS) is characterized by severe infant-onset myoclonic epilepsy along with delayed psychomotor development and heightened premature mortality.A primary monogenic cause is mutation of the SCN1A gene, which encodes the voltage-gated sodium channel subunit Nav1.1.The nature and timing of changes caused by SCN1A mutation

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Protective efficacy of an inactivated vaccine against Rabbit hemorrhagic disease virus 2 prepared from a local isolate in Egypt

Rabbit hemorrhagic disease is a contagious viral disease of rabbits controlled by vaccination.The present study was aimed to diagnose rabbit hemorrhagic disease from 11 infected farms from Qalubia governorate during 2019 and to prepare homologous vaccine against rabbit hemorrhagic disease virus 2.For this purpose, 11 liver samples were collected fr

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THE POLITICS OF BENEVOLENCE: Political Patronage of Party-based Charitable Organizations in Contemporary Indonesian Islam

The rise of party-based Islamic charities has had a profound impact on the nature of philanthropic activities in contemporary Indonesia, and stimulated a new debate over the issue of the politics of benevolent acts.Over the past few years, in line with the increase of the influence of the Islamic factor in Indonesian politics, there have been a num

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PEEP in non invasive ventilatory treatment of worsened BPCO

Acute respiratory failure due to exacerbation of chronic pulmonary disease is usually treated with bilevel pressure non invasive ventilation.An high inspiratory pressure is used to improve tidal Curry Paste volume, a lower expiratory pressure is used to neutralize end expiratory positive pressure of patient (PEEPi) caused by flow limitation and air

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